Lipophilicity represents arguably the biggest risk factor in small molecule drug design and as…
Category:
Introductory
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IntroductoryKey Concept
Which Amino Acid is the Strongest H-Bonder
by Darryl B McConnell 5 minutes readWhen analyzing a drug binding pocket it is important to assess which amino acid…
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Non-covalent molecular interactions in an aqueous environment and the resulting Gibbs free energy of…
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William Ripka, one of the pioneers of structure-based drug design, highlighted the conceptual simplicity…
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In preparing my first medicinal chemistry course at the University of Vienna I wanted…