Introductory

Lipophilicity represents arguably the biggest risk factor in small molecule drug design and as…

When analyzing a drug binding pocket it is important to assess which amino acid…

Non-covalent molecular interactions in an aqueous environment and the resulting Gibbs free energy of…

William Ripka, one of the pioneers of structure-based drug design, highlighted the conceptual simplicity…

In preparing my first medicinal chemistry course at the University of Vienna I wanted…